Author's response to reviews Title: High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children Authors:
نویسندگان
چکیده
Kathryn E Holt ([email protected]) Stephen Baker ([email protected]) Sabina Dongol ([email protected]) Buddha Basnyat ([email protected]) Neelam Adhikari ([email protected]) Stephen Thorson ([email protected]) Anoop Pulickal ([email protected]) Yajun Song ([email protected]) Julian Parkhill ([email protected]) Jeremy J Farrar ([email protected]) David R Murdoch ([email protected]) Dominic F Kelly ([email protected]) Andrew J Pollard ([email protected]) Gordon Dougan ([email protected])
منابع مشابه
High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children
BACKGROUND Salmonella Typhi (S. Typhi) causes typhoid fever, which remains an important public health issue in many developing countries. Kathmandu, the capital of Nepal, is an area of high incidence and the pediatric population appears to be at high risk of exposure and infection. METHODS We recently defined the population structure of S. Typhi, using new sequencing technologies to identify ...
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Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children
BACKGROUND Salmonella enterica serovar Typhi (S. Typhi) is a human-specific pathogen that causes typhoid fever, and remains a global health problem especially in developing countries. Its pathogenesis is complex and host response is poorly understood. In Africa, typhoid fever can be a major cause of morbidity in young infected children. The onset of the illness is insidious and clinical diagnos...
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Background: Crinum purpurascens is a herbaceous plant belonging to the Amaryllidaceae family. We aimed to evaluate the antisalmonellal properties of the leaf extracts and fractions of C. purpurascens, and the toxicity of the most active extract. Methods: Three extracts and three fractions were prepared from the leaves of Crinum purpurascens Herb. (Amaryllidaceae) and tested for their antisalmon...
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